The human HYMAI/PLAGL1 differentially methylated region acts as an imprint control region in mice
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چکیده
منابع مشابه
Methylation Status of H19/IGF2 Differentially Methylated Region in in vitro Human Blastocysts Donated by Healthy Couples
Backgrund: Imprinted genes are a unique subset of few genes, which have been differentially methylated region (DMR) in a parental origin-dependent manner during gametogenesis, and these genes are highly protected during pre-implantation epigenetic reprogramming. Several studies heve shown that the particular vulnerability of imprinting genes during suboptimal pre- and peri-conception microenvir...
متن کاملmethylation status of h19/igf2 differentially methylated region in in vitro human blastocysts donated by healthy couples
backgrund: imprinted genes are a unique subset of few genes, which have been differentially methylated region (dmr) in a parental origin-dependent manner during gametogenesis, and these genes are highly protected during pre-implantation epigenetic reprogramming. several studies heve shown that the particular vulnerability of imprinting genes during suboptimal pre- and peri-conception microenvir...
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چکیده ندارد.
15 صفحه اول(revitalizing silk road corridor in the region (north east of iran
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15 صفحه اولDeletion of Gtl2, imprinted non-coding RNA, with its differentially methylated region induces lethal parent-origin-dependent defects in mice.
The cluster of imprinted genes located in the Dlk1-Dio3 domain spanning 1 Mb plays an essential role in controlling pre- and postnatal growth and differentiation in mice and humans. The failure of parent-of-origin-dependent gene expression in this domain results in grave disorders, leading to death in some cases. However, little is known about the role of maternally expressed non-coding RNAs (n...
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ژورنال
عنوان ژورنال: Genomics
سال: 2006
ISSN: 0888-7543
DOI: 10.1016/j.ygeno.2006.07.005